SCHEMBL21323397

SCHEMBL21323397

CCCc1cc(CC)n[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.52
HCAR3 P49019 4/20 0.47
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
CCNA1 P78396 1/20 0.39
KCNH2 Q12809 4/20 0.38
GRIN2B Q13224 2/20 0.38
GLA P06280 1/20 0.33
MPO P05164 1/20 0.33
TPO P07202 1/20 0.33
TSHR P16473 1/20 0.33
LPO P22079 1/20 0.33
CYP2C19 P33261 1/20 0.33
TAS2R38 P59533 1/20 0.33
MAPT P10636 2/20 0.33
COMT P21964 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
GFER P55789 1/20 0.33
BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2765737 0.89 HCAR2 (0.53) HCAR2HCAR3CCNA2CDK2CCNA1
SCHEMBL27813837 0.88 HCAR2 (0.54) HCAR2HCAR3KCNH2GRIN2BTSHR
SCHEMBL1205841 0.84
SCHEMBL17493883 0.83 HCAR2 (0.53) HCAR2HCAR3CCNA2CDK2CCNA1
SCHEMBL19398605 0.83 HCAR2 (0.49) HCAR2HCAR3CCNA2CDK2CCNA1
SCHEMBL5689957 0.83 HCAR2 (0.50) HCAR2HCAR3CCNA2CDK2CCNA1
Hydrochloric Acid SCHEMBL17493874 0.82 HCAR2 (0.47) HCAR2HCAR3CCNA2CDK2CCNA1
SCHEMBL1205224 0.80 HCAR2 (0.46) HCAR2HCAR3CCNA2CDK2CCNA1
SCHEMBL28138793 0.78
SCHEMBL26110402 0.77 HCAR2 (0.47) HCAR2HCAR3CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924660-A Preparation method and application of emulsifier applied to acidic resin emulsification 襄阳精信汇明科技股份有限公司 2024-04-26 CN claimed
CN-115746775-A Preparation method of thermosetting polyurethane pressure-sensitive adhesive 浙江拓锐新材料科技有限公司 2023-03-07 CN claimed
CN-115558454-A Preparation method of thermosetting polyurethane pressure-sensitive adhesive 浙江拓锐新材料科技有限公司 2023-01-03 CN claimed
CN-115491160-A Preparation method of waterborne polyurethane hot melt adhesive 浙江拓锐新材料科技有限公司 2022-12-20 CN claimed
CN-114836163-A Water-based closed polyurethane adhesive and preparation method and application thereof 上海华峰新材料研发科技有限公司 2022-08-02 CN claimed
CN-107793544-B A kind of environment-friendly polyurethane curing agent and its preparation method and application 佛山市精信汇明科技有限公司 2019-09-20 CN claimed
CN-107793544-A A kind of environment-friendly polyurethane curing agent and its preparation method and application 佛山市精信汇明科技有限公司 2018-03-13 CN claimed
CN-104130375-B Polyacrylate modified watersoluble closed type isocyanate curing agent and preparation method thereof 中国海洋石油总公司 2016-08-31 CN claimed
CN-114836163-B Water-based closed polyurethane adhesive and preparation method and application thereof 上海华峰新材料研发科技有限公司 2024-04-30 CN disclosed
CN-117924660-A Preparation method and application of emulsifier applied to acidic resin emulsification 襄阳精信汇明科技股份有限公司 2024-04-26 CN disclosed
CN-115746775-A Preparation method of thermosetting polyurethane pressure-sensitive adhesive 浙江拓锐新材料科技有限公司 2023-03-07 CN disclosed
CN-115558454-A Preparation method of thermosetting polyurethane pressure-sensitive adhesive 浙江拓锐新材料科技有限公司 2023-01-03 CN disclosed
CN-115491160-A Preparation method of waterborne polyurethane hot melt adhesive 浙江拓锐新材料科技有限公司 2022-12-20 CN disclosed
CN-114836163-A Water-based closed polyurethane adhesive and preparation method and application thereof 上海华峰新材料研发科技有限公司 2022-08-02 CN disclosed
CN-111423343-A Hydrophilic diisocyanate and preparation method and application thereof 佛山市精信汇明科技有限公司 2020-07-17 CN disclosed
CN-107793544-B A kind of environment-friendly polyurethane curing agent and its preparation method and application 佛山市精信汇明科技有限公司 2019-09-20 CN disclosed
EP-2900669-B1 HEXAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AND RELATED COMPOUNDS AS AUTOTAXIN (ATX) INHIBITORS AND AS INHIBITORS OF THE LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION FOR TREATING E.G. RENAL DISEASES HOFFMANN LA ROCHE (CH) 2019-09-04 EP disclosed
CN-109897160-A Blocked polyurethane curing agent emulsion and preparation method and application thereof 襄阳精信汇明科技股份有限公司 2019-06-18 CN disclosed
CN-107793544-A A kind of environment-friendly polyurethane curing agent and its preparation method and application 佛山市精信汇明科技有限公司 2018-03-13 CN disclosed
CN-104130375-B Polyacrylate modified watersoluble closed type isocyanate curing agent and preparation method thereof 中国海洋石油总公司 2016-08-31 CN disclosed