⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324893 | 0.87 | — | — | |
| SCHEMBL24952528 | 0.73 | — | — | |
| SCHEMBL19543655 | 0.71 | POLB (0.31) | — | |
| SCHEMBL21325293 | 0.68 | — | — | |
| SCHEMBL21533953 | 0.66 | — | — | |
| SCHEMBL23583314 | 0.60 | — | — | |
| SCHEMBL21627160 | 0.60 | KDM4E (0.31) | — | |
| SCHEMBL611663 | 0.60 | POLB (0.35) | — | |
| SCHEMBL9914394 | 0.60 | — | — | |
| SCHEMBL13698409 | 0.60 | POLB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174271-B2 | 6-membered uracil isosteres | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2021-11-16 | — | — | US | disclosed |
| US-20190270756-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2019-09-05 | — | — | US | disclosed |