Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.35 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714621 | 0.88 | CYP2B6 (0.33) | CYP2B6TENT4ATENT4BFGFR4KCNH2 | |
| SCHEMBL21327217 | 0.88 | CYP2B6 (0.33) | CYP2B6TENT4ATENT4BFGFR4KCNH2 | |
| SCHEMBL21327297 | 0.86 | CYP2B6 (0.35) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL21461928 | 0.81 | CYP2B6 (0.33) | CYP2B6TENT4ATENT4BFGFR4 | |
| SCHEMBL21327464 | 0.75 | CYP2B6 (0.33) | CYP2B6TENT4ATENT4B | |
| SCHEMBL21327168 | 0.74 | CYP2B6 (0.37) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL2811767 | 0.74 | CA1 (0.40) | KDM4EUSP2KMT2AALDH1A1 | |
| SCHEMBL2806187 | 0.74 | LPAR1 (0.36) | KDM4EALDH1A1LPAR1 | |
| SCHEMBL21474401 | 0.73 | HTR2A (0.37) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL21327250 | 0.70 | CYP2B6 (0.37) | CYP2B6TENT4ATENT4BFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534903-A1 | SUBSTITUTED PYRIDINONE-CONTAINING TRICYCLIC COMPOUNDS, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2019-09-11 | — | — | EP | disclosed |