Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408876 | 0.92 | SLC22A12 (0.59) | SLC22A12CYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL21350619 | 0.86 | KDM4E (0.47) | SLC22A12CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL21350744 | 0.84 | SLC22A12 (0.51) | SLC22A12CYP2C9CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL21350742 | 0.83 | SLC22A12 (0.50) | SLC22A12CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL28415846 | 0.83 | SLC22A12 (0.50) | SLC22A12CYP2C9CYP1A2ALDH1A1HTT | |
| SCHEMBL21331815 | 0.83 | SLC22A12 (0.53) | SLC22A12CYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL21350526 | 0.82 | SLC22A12 (0.68) | SLC22A12SLC22A11 | |
| SCHEMBL21331811 | 0.82 | SLC22A12 (0.55) | SLC22A12CYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL21331877 | 0.81 | SLC22A12 (0.51) | SLC22A12CYP2C9CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL28890905 | 0.81 | SLC22A12 (0.54) | SLC22A12CYP2C9CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | claimed |
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |