Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 3/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332347 | 0.89 | CYP3A4 (0.44) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL17599833 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL19448747 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL17680645 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL17599836 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL24420028 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL17599796 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL12646814 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL10082621 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL17599882 | 0.86 | CYP3A4 (0.60) | CYP3A4MAPTCYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762395-A1 | NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME | Sanofi (FR) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019170731-A1 | NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME | SANOFI (FR) | 2019-09-12 | — | — | WO | disclosed |