SCHEMBL21332769

SCHEMBL21332769

Cn1nc(Cl)c2cncnc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.39
PI4K2B Q8TCG2 1/20 0.39
PI4K2A Q9BTU6 1/20 0.39
PI4KB Q9UBF8 1/20 0.39
CYP1A2 P05177 2/20 0.35
USP2 O75604 1/20 0.35
TSHR P16473 1/20 0.35
GRM4 Q14833 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALOX15 P16050 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
NSD2 O96028 1/20 0.33
PKM P14618 1/20 0.33
GSK3B P49841 1/20 0.33
CYP2C9 P11712 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NR3C1 P04150 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10151404 0.80 ADORA2A (0.41) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL27228398 0.78 PI4KA (0.38) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL20674200 0.78 PI4KB (0.38) PI4KAPI4K2BPI4K2API4KBGRM4
SCHEMBL30861079 0.78 PI4KB (0.55) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL27228218 0.78 PI4KB (0.55) PI4KAPI4K2BPI4K2API4KBCYP1A2
Ammonia Solution, Strong SCHEMBL23150476 0.78 ADORA2A (0.39) PI4KAPI4K2BPI4K2API4KBCYP1A2
SCHEMBL29582154 0.76 PI4KA (0.36) PI4KAPI4K2BPI4K2API4KBSMN1; SMN2
SCHEMBL24828099 0.72 CYP1A2 (0.50) CYP1A2USP2TSHRSMN1; SMN2ALOX15
SCHEMBL31149372 0.72 HSD17B10 (0.42) GSK3BHSD17B10NR3C1MEN1KMT2A
SCHEMBL29026871 0.72 GSK3B (0.43) PI4KAPI4K2BPI4K2API4KBGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242880-A1 THERAPEUTIC COMPOUNDS AND THEIR USE MY-T BIO LIMITED (GB) 2025-11-27 WO disclosed
EP-3952902-A1 DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS Pliant Therapeutics, Inc. (US) 2022-02-16 EP disclosed
EP-3761980-A1 AMINO ACID COMPOUNDS AND METHODS OF USE Pliant Therapeutics, Inc. (US) 2021-01-13 EP disclosed
WO-2020210404-A1 DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS PLIANT THERAPEUTICS, INC. (US) 2020-10-15 WO disclosed
WO-2019173653-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. (US) 2019-09-12 WO disclosed