Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28324886 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL213351 | 1.00 | — | — | |
| Bicarbonate SCHEMBL21633872 | 1.00 | — | — | |
| Bicarbonate SCHEMBL213349 | 1.00 | — | — | |
| Bicarbonate SCHEMBL892510 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5897106 | 0.93 | — | — | |
| Bicarbonate SCHEMBL20553822 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21352703 | 0.93 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL16228229 | 0.93 | — | — | |
| Bicarbonate SCHEMBL6946379 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2117 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260107466-A1 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD OF A SEMICONDUCTOR DEVICE | SK Hynix Inc. (KR) | 2026-04-16 | — | — | US | claimed |
| US-20260107435-A1 | SEMICONDUCTOR DEVICE AND METHOD FOR FABRICATING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-04-16 | — | — | US | claimed |
| US-20260096113-A1 | CAPACITOR STRUCTURE, MEMORY DEVICE AND MANUFACTURING METHOD THEREOF | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-04-02 | — | — | US | claimed |
| US-12588199-B2 | Non-volatile memory device and electronic system including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-03-24 | — | — | US | claimed |
| EP-3970914-B1 | DEVICE FOR APPLYING A MAGNETIC FIELD TO A MAGNETORHEOLOGICAL FLUID, SYSTEM AND METHOD FOR PROCESSING A WORKPIECE USING THE MAGNETORHEOLOGICAL FLUID | FRAUNHOFER GES FORSCHUNG (DE) | 2026-03-11 | — | — | EP | claimed |
| US-12571069-B2 | Method for the recovery of metals from electronic waste | SMS GROUP GMBH (DE) | 2026-03-10 | — | — | US | claimed |
| US-20250351468-A1 | Method for Contacting the Gates of a Spin Qubit Gate Array | IMEC VZW (BE) | 2025-11-13 | — | — | US | claimed |
| EP-4648092-A1 | A METHOD FOR CONTACTING THE GATES OF A SPIN QUBIT GATE ARRAY | Imec VZW (BE) | 2025-11-12 | — | — | EP | claimed |
| US-20250266358-A1 | SEMICONDUCTOR MEMORY DEVICE | KIOXIA CORPORATION (JP) | 2025-08-21 | — | — | US | claimed |
| CN-119615399-B | Preparation method of acid and alkali resistant regenerated yarn | 江苏佩浦高分子科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| US-5085776-A | Used for gas, vapor or pervaporation | MEMBRANE TECHNOLOGY & RESEARCH, INC. (US) | 1992-02-04 | — | — | US | claimed |
| EP-0459918-A1 | Conductive substrate and printing media using the same | TOMOEGAWA PAPER CO. LTD. (JP) | 1991-12-04 | — | — | EP | claimed |
| WO-1991004292-A1 | ABSORBENT MATERIAL AND USES THEREOF | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1991-04-04 | — | — | WO | claimed |
| US-4990255-A | Calibrating thickness of permselective layer; high performance | MEMBRANE TECHNOLOGY & RESEARCH INC. (US) | 1991-02-05 | — | — | US | claimed |
| EP-0403275-A2 | A magnetic recording medium | KONICA CORPORATION (JP) | 1990-12-19 | — | — | EP | claimed |
| EP-0382557-A1 | Dielectric material | JUNKOSHA CO. LTD. (JP) | 1990-08-16 | — | — | EP | claimed |
| US-4931181-A | Composite membranes for fluid separations | MEMBRANE TECHNOLOGY & RESEARCH, INC. (US) | 1990-06-05 | — | — | US | claimed |
| US-4763995-A | Spacers with alignment effect and substrates having a weak alignment effect | CANON KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | claimed |
| EP-0009978-B1 | HYBRID TYPE INTEGRATED CIRCUIT DEVICE | Hitachi, Ltd. (JP) | 1984-04-18 | — | — | EP | claimed |
| EP-0009978-A1 | Hybrid Type integrated circuit device | Hitachi, Ltd. (JP) | 1980-04-16 | — | — | EP | claimed |