⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL212712 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL1258481 | 0.95 | — | — | |
| Bromide SCHEMBL21049419 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL7365593 | 0.95 | — | — | |
| Bicarbonate SCHEMBL17423403 | 0.84 | — | — | |
| SCHEMBL31461747 | 0.82 | — | — | |
| SCHEMBL10424357 | 0.70 | — | — | |
| SCHEMBL160546 | 0.70 | — | — | |
| SCHEMBL3074219 | 0.70 | — | — | |
| SCHEMBL5174178 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417906-A | Recombinant microorganism and its use in the production of nucleosides | 廊坊梅花生物技术开发有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-113383039-B | Moisture curable polyolefin formulation | 陶氏环球技术有限责任公司 | 2023-09-26 | — | — | CN | claimed |
| CN-113481139-B | Recombinant bacillus subtilis for producing glycocyamine and construction method thereof | 江南大学 | 2022-11-08 | — | — | CN | claimed |
| US-20220098432-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-03-31 | — | — | US | claimed |
| EP-3924419-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | Dow Global Technologies LLC (US) | 2021-12-22 | — | — | EP | claimed |
| CN-113383039-A | Moisture curable polyolefin formulations | 陶氏环球技术有限责任公司 | 2021-09-10 | — | — | CN | claimed |
| CN-112408628-A | Method for treating uranium and manganese containing industrial wastewater | 核工业北京化工冶金研究院 | 2021-02-26 | — | — | CN | claimed |
| WO-2020164004-A1 | MOISTURE-CURABLE POLYOLEFIN FORMULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-20 | — | — | WO | claimed |
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | claimed |
| US-20050020659-A1 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | claimed |
| WO-2004098589-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | claimed |
| US-6803464-B2 | REACTING ACID SALT OF AMINOACETAMIDINE WITH A SOURCE-OF CYANIDE AND REACTING WITH 2,3,5-TRICHLOROBENZALDEHYDE TO PRODUCE 2-((CYANO-(2,3,5-TRICHLOROPHENYL)-METHYL)-AMINO)-ACETAMIDINE OR A SALT THEREOF | SMITHKLINE BEECHAM CORPORATION | 2004-10-12 | — | — | US | claimed |
| JP-2003532702-A | — | — | 2003-11-05 | — | — | JP | claimed |
| US-20030149053-A1 | Process for the preparation of pyrazine compounds | Jazz Pharmaceuticals, Inc. | 2003-08-07 | — | — | US | claimed |
| EP-1278721-A1 | PROCESS FOR THE PREPARATION OF PYRAZINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2003-01-29 | — | — | EP | claimed |
| WO-2001085674-A1 | PROCESS FOR THE PREPARATION OF PYRAZINE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2001-11-15 | — | — | WO | claimed |
| EP-0389437-B1 | Luciferin derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1995-05-24 | — | — | EP | claimed |
| EP-0047412-B1 | PYRAZINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1984-07-25 | — | — | EP | claimed |
| EP-0047412-A1 | Pyrazines, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1982-03-17 | — | — | EP | claimed |