Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806425 | 0.92 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| Hydrochloric Acid SCHEMBL16783635 | 0.91 | PIK3CD (0.36) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3C2B | |
| SCHEMBL21337803 | 0.89 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| Formic Acid SCHEMBL16783586 | 0.88 | PIK3CD (0.35) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3C2B | |
| SCHEMBL21337762 | 0.87 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21337788 | 0.87 | ATR (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL21337670 | 0.87 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL16783407 | 0.85 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL16783612 | 0.85 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL21337782 | 0.85 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | disclosed |