Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.56 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.56 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340104 | 0.94 | MTOR (0.58) | MTORRPTORMLST8KDM4EGRM1 | |
| SCHEMBL21360296 | 0.90 | MTOR (0.69) | MTORRPTORMLST8KDM4ETP53 | |
| SCHEMBL22664833 | 0.89 | MTOR (0.68) | MTORRPTORMLST8GRM1SMN1; SMN2 | |
| SCHEMBL22664832 | 0.87 | MTOR (0.63) | MTORRPTORMLST8KDM4EGRM1 | |
| SCHEMBL21360298 | 0.84 | MTOR (0.64) | MTORRPTORMLST8KDM4ETP53 | |
| SCHEMBL21360295 | 0.84 | MTOR (0.64) | MTORRPTORMLST8KDM4ETP53 | |
| SCHEMBL22159438 | 0.84 | KDM4E (0.40) | MTORRPTORMLST8KDM4EGRM1 | |
| SCHEMBL22693124 | 0.83 | MTOR (0.72) | MTORRPTORMLST8KDM4ESMN1; SMN2 | |
| SCHEMBL22664841 | 0.83 | MTOR (0.68) | MTORRPTORMLST8 | |
| SCHEMBL20141125 | 0.80 | MTOR (0.80) | MTORRPTORMLST8KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.