Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342738 | 0.98 | TSHR (0.46) | TSHRALDH1A1LMNAHRH4HRH3 | |
| SCHEMBL18639691 | 0.98 | TSHR (0.46) | TSHRALDH1A1LMNAHRH4HRH3 | |
| SCHEMBL14773334 | 0.93 | TSHR (0.42) | TSHRALDH1A1LMNAHRH4HRH3 | |
| SCHEMBL7834390 | 0.79 | HRH4 (0.43) | TSHRALDH1A1HRH4HRH3POLB | |
| SCHEMBL7678099 | 0.76 | TSHR (0.42) | TSHRALDH1A1HRH4HRH3POLB | |
| SCHEMBL14176497 | 0.76 | HRH4 (0.45) | ALDH1A1HRH4HRH3POLB | |
| SCHEMBL13884243 | 0.76 | HRH4 (0.45) | ALDH1A1HRH4HRH3POLB | |
| SCHEMBL13884273 | 0.76 | HRH4 (0.45) | ALDH1A1HRH4HRH3POLB | |
| SCHEMBL13884287 | 0.76 | HRH4 (0.45) | ALDH1A1HRH4HRH3POLB | |
| SCHEMBL1276622 | 0.76 | HRH4 (0.45) | ALDH1A1HRH4HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173640-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INSULIN RESISTANCE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-09-12 | — | — | WO | disclosed |