⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761804 | 0.69 | — | — | |
| Hydrogen Sulfide SCHEMBL28746193 | 0.67 | — | — | |
| SCHEMBL29416661 | 0.65 | — | — | |
| SCHEMBL30043153 | 0.65 | — | — | |
| SCHEMBL15068302 | 0.63 | — | — | |
| SCHEMBL3372716 | 0.62 | — | — | |
| SCHEMBL3373449 | 0.62 | — | — | |
| SCHEMBL19720137 | 0.61 | — | — | |
| SCHEMBL8697930 | 0.59 | — | — | |
| SCHEMBL31454341 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | UNIV LELAND STANFORD JUNIOR (US) | 2024-07-18 | — | — | US | disclosed |
| US-20230374017-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2023-11-23 | — | — | US | disclosed |
| CN-116249531-A | Compositions and methods for activating pyruvate kinase | 密执安大学评议会 | 2023-06-09 | — | — | CN | disclosed |
| EP-4185293-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | The Regents of The University of Michigan (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2023081261-A1 | TUNABLE FLUORESCENT COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-05-11 | — | — | WO | disclosed |
| US-20210196716-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2021-07-01 | — | — | US | disclosed |
| EP-3697354-A1 | COMPOSITIONS AND METHODS FOR TREATING EYE DISORDERS | The Regents of The University of Michigan (US) | 2020-08-26 | — | — | EP | disclosed |
| US-10675364-B2 | Rhodol fluorophores for near-infrared imaging | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-10570150-B2 | 6,7-trans cephalosporin-based probes for detecting bacteria expressing a metallo-beta-lactamase | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-10441588-B2 | Methods and compositions for treating bacterial infection | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-10-15 | — | — | US | disclosed |
| WO-2000035435-A1 | USE OF A MEK INHIBITOR FOR PREVENTING TRANSPLANT REJECTION | WARNER-LAMBERT COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0993437-A1 | 2-(4-BROMO OR 4-IODO PHENYLAMINO) BENZOIC ACID DERIVATIVES AND THEIR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| EP-0993439-A1 | 4-BROMO OR 4-IODO PHENYLAMINO BENZHYDROXAMIC ACID DERIVATIVES AND THEIR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-04-19 | — | — | EP | disclosed |
| US-5994495-A | Selectively functionalizable desdendrimers | DIBRA S.P.A. (IT) | 1999-11-30 | — | — | US | disclosed |
| WO-1999001421-A1 | 2-(4-BROMO OR 4-IODO PHENYLAMINO) BENZOIC ACID DERIVATIVES AND THEIR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001426-A1 | 4-BROMO OR 4-IODO PHENYLAMINO BENZHYDROXAMIC ACID DERIVATIVES AND THEIR USE AS MEK INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |
| US-5807971-A | CORE WITH POLYOXAALKYLENE BRANCHES | DIBRA S.P.A. (IT) | 1998-09-15 | — | — | US | disclosed |
| WO-1998037881-A1 | METHOD OF TREATING OR PREVENTING SEPTIC SHOCK BY ADMINISTERING A MEK INHIBITOR | WARNER LAMBERT COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |
| EP-0850262-A1 | SELECTIVELY FUNCTIONALIZABLE DESDENDRIMERS | BRACCO S.p.A. (IT) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997010281-A1 | SELECTIVELY FUNCTIONALIZABLE DESDENDRIMERS | BRACCO S.P.A. (IT) | 1997-03-20 | — | — | WO | disclosed |