Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 8/20 | 0.38 |
| ▸ | JAK2 | O60674 | 7/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22941608 | 0.88 | JAK1 (0.36) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21343740 | 0.86 | MEN1 (0.36) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL21361256 | 0.86 | GRIN2B (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21361224 | 0.84 | JAK1 (0.39) | JAK1JAK2IRAK4JAK3 | |
| SCHEMBL21343905 | 0.83 | FFAR4 (0.32) | MEN1ALDH1A1KMT2ATSHRNPSR1 | |
| SCHEMBL21361221 | 0.82 | USP2 (0.40) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL22992131 | 0.81 | IRAK4 (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21361223 | 0.81 | JAK2 (0.37) | JAK1JAK2IRAK4JAK3 | |
| SCHEMBL24426540 | 0.81 | MEN1 (0.33) | MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL21344722 | 0.81 | HSP90AA1 (0.36) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |