Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | TTPA | P49638 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15851246 | 0.89 | MAPT (0.41) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL15854991 | 0.87 | PSEN1 (0.43) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL15851242 | 0.84 | MAPT (0.55) | MEN1KMT2AMAPTLMNAGSTP1 | |
| SCHEMBL21344345 | 0.83 | MEN1 (0.38) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346383 | 0.82 | MEN1 (0.46) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346932 | 0.82 | MEN1 (0.48) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346571 | 0.80 | PSEN1 (0.50) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346572 | 0.80 | MEN1 (0.52) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL14544421 | 0.79 | PSEN1 (0.50) | MEN1KMT2APDE4APDE3AGSTO1 | |
| SCHEMBL10346399 | 0.79 | MEN1 (0.46) | MEN1KMT2APDE4APDE3AGSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019171088-A1 | BIOISPIRED PROTEASOME ACTIVATORS WITH ANTIAGEING ACTIVITY | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2019-09-12 | — | — | WO | disclosed |