Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684394 | 0.87 | PDK2 (0.33) | PDE4DPDK2 | |
| SCHEMBL449262 | 0.87 | PDK2 (0.33) | PDE4DPDK2 | |
| SCHEMBL6007286 | 0.78 | PDK2 (0.41) | PDK2 | |
| SCHEMBL6006546 | 0.78 | PDK2 (0.41) | PDK2 | |
| SCHEMBL21344814 | 0.75 | EGFR (0.35) | PDE4D | |
| SCHEMBL2710475 | 0.74 | ESR1 (0.38) | PDE4D | |
| SCHEMBL3146501 | 0.74 | MAPT (0.50) | PDE4D | |
| SCHEMBL21344806 | 0.72 | BCL2 (0.50) | PDK2 | |
| SCHEMBL20942083 | 0.71 | ESR1 (0.50) | PDK2 | |
| SCHEMBL4271007 | 0.71 | ESR1 (0.50) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953369-B2 | Spirocentric compounds and polymers thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190276454-A1 | Spirocentric Compounds and Polymers Thereof | GEORGIA TECH RESEARCH CORPORATION | 2019-09-12 | — | — | US | disclosed |
| WO-2019173646-A1 | SPIROCENTRIC COMPOUNDS AND POLYMERS THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276454-A1 | Spirocentric Compounds and Polymers Thereof | PKD1, PKD2, VIM | PDE4D 956/4885PDK2 1984/4885 |
| US-10953369-B2 | Spirocentric compounds and polymers thereof | PKD1, PKD2, VIM | PDE4D 956/4885PDK2 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.