Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727451 | 0.94 | MEN1 (0.48) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3727450 | 0.94 | MEN1 (0.48) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3777963 | 0.83 | CYP17A1 (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3777965 | 0.83 | CYP17A1 (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13062960 | 0.83 | CYP17A1 (0.40) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3778074 | 0.79 | POLB (0.43) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3778070 | 0.79 | POLB (0.43) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL13785800 | 0.79 | POLB (0.43) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL21017931 | 0.78 | KDM4E (0.44) | MAPTKDM4ERAB9ANPC1GLA | |
| SCHEMBL10092627 | 0.78 | CYP17A1 (0.48) | SMN1; SMN2MAP4K4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173270-A1 | ANTIMICROBIAL POLY(GUANYLUREA)S | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2019-09-12 | — | — | WO | disclosed |