Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255630 | 0.97 | HRH3 (0.66) | HRH3NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL21347483 | 0.84 | HRH3 (0.68) | HRH3NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL21347499 | 0.83 | HRH3 (0.66) | HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL21348251 | 0.83 | HRH3 (0.66) | HRH3NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL26010198 | 0.82 | HRH3 (0.53) | HRH3SMN1; SMN2KDM4E | |
| SCHEMBL12981 | 0.82 | HRH3 (0.69) | HRH3SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL31546411 | 0.82 | HRH3 (0.69) | HRH3SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL3044721 | 0.82 | MAOB (0.64) | HRH3NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL26010164 | 0.81 | HRH3 (0.69) | HRH3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL28255638 | 0.81 | HRH3 (0.91) | HRH3NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762364-B1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-23 | — | — | EP | disclosed |
| WO-2019170115-A1 | PYRROLIDINEAMIDE DERIVATIVES AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-09-12 | — | — | WO | disclosed |