Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 12/20 | 0.44 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21349073 | 1.00 | OGA (0.44) | OGAHEXB | |
| SCHEMBL21348403 | 1.00 | OGA (0.44) | OGAHEXB | |
| SCHEMBL12417938 | 0.87 | OGA (0.36) | OGA | |
| SCHEMBL14556012 | 0.84 | OGA (0.42) | OGAHEXB | |
| SCHEMBL10026361 | 0.83 | OGA (0.42) | OGA | |
| SCHEMBL20280297 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL19938156 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL14447610 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL12972236 | 0.81 | OGA (0.41) | OGA | |
| SCHEMBL13575271 | 0.81 | OGA (0.41) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2019173682-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | ARCUS BIOSCIENCES, INC. (US) | 2019-09-12 | — | — | WO | disclosed |