SCHEMBL21348880

SCHEMBL21348880

N[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 1.00
FUCA1 P04066 4/20 0.56
LMNA P02545 1/20 0.50
APP P05067 1/20 0.50
SI P14410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL371513 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL371514 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL247045 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL29885626 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL371512 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL371511 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL14007131 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL15926078 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL10824967 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI
SCHEMBL11348573 1.00 GBA1 (1.00) GBA1FUCA1LMNAAPPSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed
WO-2019173293-A1 AFFINITY PURIFICATION OF GLYCOSIDE-CLEAVING ENZYMES SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2019-09-12 WO disclosed