Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 12/20 | 0.39 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356538 | 0.95 | P2RY12 (0.36) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18927171 | 0.91 | P2RY12 (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18917301 | 0.91 | P2RY12 (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18797869 | 0.86 | TYMP (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18927156 | 0.86 | P2RY12 (0.45) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL22219978 | 0.86 | P2RY12 (0.35) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL19762770 | 0.85 | P2RY12 (0.41) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL22879142 | 0.85 | P2RY12 (0.36) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL18048087 | 0.85 | TYMP (0.39) | P2RY12DNPH1P2RY2P2RY1P2RY6 | |
| SCHEMBL19250015 | 0.85 | P2RY12 (0.41) | P2RY12DNPH1P2RY2P2RY1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| EP-3765474-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2020-04-02 | — | — | US | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | P2RY12 1378/4885DNPH1 4434/4885P2RY2 964/4885 |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | P2RY12 1378/4885DNPH1 4434/4885P2RY2 964/4885 |
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | P2RY12 1378/4885DNPH1 4434/4885P2RY2 964/4885 |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | P2RY12 1378/4885DNPH1 4434/4885P2RY2 964/4885 |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | P2RY12 1378/4885DNPH1 4434/4885P2RY2 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.