Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356334 | 0.89 | ADORA2A (0.43) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL20337206 | 0.89 | TYMP (0.43) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL20353027 | 0.89 | TYMP (0.43) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL20348400 | 0.86 | TYMP (0.41) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL21356527 | 0.86 | ADORA2A (0.40) | ADORA2AADORA2BTYMPADORA1PRMT6 | |
| SCHEMBL20353032 | 0.86 | TYMP (0.43) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL20337209 | 0.86 | TYMP (0.43) | ADORA2AADORA2BTYMPADORA1 | |
| SCHEMBL20348406 | 0.83 | TYMP (0.41) | ADORA2AADORA2BTYMP | |
| SCHEMBL21356506 | 0.83 | TYMP (0.47) | TYMP | |
| SCHEMBL20482910 | 0.82 | TYMP (0.55) | ADORA2AADORA2BTYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| EP-3765474-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2020-04-02 | — | — | US | disclosed |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2019-09-19 | — | — | US | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | ADORA2A 1183/4885ADORA2B 1539/4885TYMP 1265/4885 |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | ADORA2A 1183/4885ADORA2B 1539/4885TYMP 1265/4885 |
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | ADORA2A 1183/4885ADORA2B 1539/4885TYMP 1265/4885 |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | ADORA2A 1183/4885ADORA2B 1539/4885TYMP 1265/4885 |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | ADORA2A 1183/4885ADORA2B 1539/4885TYMP 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.