SCHEMBL213568

SCHEMBL213568

C[Si](C)(C)ON=C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
MEN1 O00255 1/20 0.32
FAAH O00519 1/20 0.32
ABHD16A O95870 1/20 0.32
KMT2A Q03164 1/20 0.32
PLA2G7 Q13093 1/20 0.32
NCEH1 Q6PIU2 1/20 0.32
DAGLB Q8NCG7 1/20 0.32
DAGLA Q9Y4D2 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212679 0.97 TSHR (0.32) TSHRCASP1NPC1RAB9ASMN1; SMN2
SCHEMBL2048923 0.87
SCHEMBL2046702 0.83
SCHEMBL2046704 0.83
SCHEMBL17257006 0.78 CHRM3 (0.30)
SCHEMBL17257008 0.78 CHRM3 (0.30)
SCHEMBL17257231 0.78 CHRM3 (0.30)
SCHEMBL17257230 0.78 CHRM3 (0.30)
SCHEMBL2045211 0.77 CYP2D6 (0.30) KMT2A
SCHEMBL2045209 0.77 CYP2D6 (0.30) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed