Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 18/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21359303 | 0.91 | OGA (0.46) | OGAOPRK1ADRA2BSLC6A4SLC6A3 | |
| SCHEMBL21370137 | 0.91 | OGA (0.46) | OGAOPRK1ADRA2BSLC6A4SLC6A3 | |
| SCHEMBL24862858 | 0.91 | OGA (0.46) | OGAOPRK1ADRA2BSLC6A4SLC6A3 | |
| SCHEMBL21370313 | 0.85 | OGA (0.53) | OGAOPRK1ADRA2BSLC6A4SLC6A3 | |
| SCHEMBL28568842 | 0.85 | OGA (0.53) | OGAOPRK1ADRA2BSLC6A4SLC6A3 | |
| SCHEMBL21359584 | 0.85 | OGA (0.58) | OGAOPRK1 | |
| SCHEMBL28569974 | 0.81 | OGA (0.37) | OGAOPRK1 | |
| SCHEMBL21369465 | 0.81 | OGA (0.37) | OGAOPRK1 | |
| SCHEMBL21369606 | 0.80 | OGA (0.42) | OGAOPRK1 | |
| SCHEMBL21359460 | 0.80 | OGA (0.39) | OGAOPRK1ADRA2BSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765458-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |