SCHEMBL21359522

SCHEMBL21359522

CC(=O)Nc1ncc(CN2CC[C@@H](C)[C@H](Cc3ncc(F)cn3)C2)s1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OGA O60502 19/20 0.56
OPRK1 P41145 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21359465 1.00 OGA (0.56) OGAOPRK1
SCHEMBL21359507 1.00 OGA (0.56) OGAOPRK1
SCHEMBL21359496 1.00 OGA (0.56) OGAOPRK1
SCHEMBL24862806 1.00 OGA (0.56) OGAOPRK1
SCHEMBL24862882 0.91 OGA (0.54) OGAOPRK1
SCHEMBL22964755 0.91 OGA (0.54) OGAOPRK1
SCHEMBL21370121 0.91 OGA (0.54) OGAOPRK1
SCHEMBL21369445 0.87 OGA (0.61) OGAOPRK1
SCHEMBL21369438 0.87 OGA (0.61) OGAOPRK1
SCHEMBL25625866 0.87 OGA (0.61) OGAOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186899-A1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS Biogen MA Inc. (US) 2023-05-31 EP disclosed
EP-3765458-B1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS BIOGEN MA INC (US) 2023-01-11 EP disclosed
EP-3765458-A1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS Biogen MA Inc. (US) 2021-01-20 EP disclosed
CN-112218863-A O-glycoprotein-2-acetamido-2-deoxy-3-D-pyranosidase inhibitors 比奥根MA公司 2021-01-12 CN disclosed
WO-2019178191-A1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS BIOGEN MA INC. (US) 2019-09-19 WO disclosed
WO-2019178191-A1 O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS BIOGEN MA INC. (US) 2019-09-19 WO disclosed