Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 12/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366151 | 0.91 | HRH1 (0.70) | HRH1KCNH2CYP2D6USP2POLB | |
| SCHEMBL18884476 | 0.91 | HRH1 (0.70) | HRH1KCNH2CYP2D6 | |
| SCHEMBL28422607 | 0.90 | HRH1 (0.71) | HRH1KCNH2CYP2D6 | |
| SCHEMBL8367704 | 0.89 | HRH1 (0.69) | HRH1KCNH2CYP2D6 | |
| Bilastine SCHEMBL991810 | 0.87 | HRH1 (0.82) | HRH1KCNH2CYP2D6USP2POLB | |
| Bilastine SCHEMBL29402994 | 0.87 | HRH1 (0.82) | HRH1KCNH2CYP2D6USP2POLB | |
| SCHEMBL28422609 | 0.86 | HRH1 (0.75) | HRH1KCNH2CYP2D6USP2POLB | |
| SCHEMBL19770379 | 0.84 | HRH1 (0.95) | HRH1KCNH2 | |
| Bilastine SCHEMBL21815518 | 0.84 | HRH1 (0.77) | HRH1KCNH2CYP2D6 | |
| SCHEMBL17888852 | 0.84 | HRH1 (0.82) | HRH1KCNH2CYP2D6USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175722-A1 | PROCESS FOR THE PREPARATION OF STABLE AND HIGHLY PURE CRYSTALLINE FORM 2 OF BILASTINE | SYMED LABS LIMITED (IN) | 2019-09-19 | — | — | WO | disclosed |