SCHEMBL21361910

SCHEMBL21361910

CC(C)(C)N=S1(=O)CCOCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26153038 0.79
SCHEMBL22932561 0.77
SCHEMBL19544967 0.77
SCHEMBL12555390 0.72
SCHEMBL24853484 0.71
SCHEMBL24539478 0.67
SCHEMBL18838268 0.67
SCHEMBL24539978 0.67
SCHEMBL19135461 0.67
SCHEMBL25468341 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 US disclosed
US-20230159527-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON BIOSCIENCES, LTD. (CN) 2023-05-25 US disclosed
US-20220402913-A1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS, LTD. (CN) 2022-12-22 US disclosed
US-11091478-B2 Apoptosis-inducing agents FOCHON PHARMACEUTICAL CO., LTD. (CN) 2021-08-17 US disclosed
US-10894052-B2 Heterocyclic inhibitors of ATR kinase BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-01-19 US disclosed
US-20200115379-A1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS, LTD. (CN) 2020-04-16 US disclosed
US-20190282584-A1 HETEROCYCLIC INHIBITORS OF ATR KINASE ARTIOS PHARMA LIMITED (GB) 2019-09-19 US disclosed