Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978587 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL9671156 | 0.80 | KDM4E (0.83) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL17481791 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL15977862 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL15978586 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL492168 | 0.76 | CACNA1B (0.66) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL5221545 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL17481794 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL1477066 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| Hydrochloric Acid SCHEMBL10806159 | 0.74 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2HRH3LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981590-B1 | LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2019-09-18 | — | — | EP | disclosed |