SCHEMBL21364546

SCHEMBL21364546

CNCCCC[C@@H](Cc1cc(C)c(F)c(C)c1)C(=O)NO

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.70
KCNH2 Q12809 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3436926 0.86 CYP2D6 (0.65) CYP2D6KCNH2
SCHEMBL3437198 0.86 CYP2D6 (0.65) CYP2D6KCNH2
SCHEMBL3437071 0.85 CYP2D6 (0.64) CYP2D6KCNH2
SCHEMBL3436932 0.84 CYP2D6 (0.77) CYP2D6KCNH2
SCHEMBL3436946 0.83 CYP2D6 (0.69) CYP2D6KCNH2
SCHEMBL3436886 0.83 CYP2D6 (1.00) CYP2D6KCNH2
SCHEMBL3436885 0.83 CYP2D6 (1.00) CYP2D6KCNH2
SCHEMBL3437190 0.83 CYP2D6 (0.84) CYP2D6KCNH2
SCHEMBL3436880 0.82 CYP2D6 (0.82) CYP2D6KCNH2
SCHEMBL3436935 0.82 CYP2D6 (0.82) CYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019178063-A1 PYRIDIN-2-YL ALKYLAMINO SUBSTITUTED HYDROXAMIC ACID AND USES THEREOF HAWAII BIOTECH, INC. (US) 2019-09-19 WO disclosed