SCHEMBL21365732

SCHEMBL21365732

CCOC(=O)CC1C(=O)Cc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
GAA P10253 1/20 0.42
ANPEP P15144 2/20 0.41
ALOX15 P16050 1/20 0.41
NOTUM Q6P988 1/20 0.41
IDO1 P14902 1/20 0.41
HTR2A P28223 5/20 0.41
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.40
HRH1 P35367 3/20 0.40
PKM P14618 1/20 0.39
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992364 0.84 CYP1A2 (0.48) CYP1A2GAANOTUMIDO1HTR2A
SCHEMBL10744543 0.84 CYP1A2 (0.52) CYP1A2GAANOTUMIDO1HTR2A
SCHEMBL13137661 0.80 ANPEP (0.47) ANPEPHTR2AHRH1HTR2C
SCHEMBL6069410 0.79 ANPEP (0.49) ANPEPHTR2AHRH1HTR2C
SCHEMBL11836856 0.77 CYP1A2 (0.46) CYP1A2GAAIDO1HTR2AHRH1
SCHEMBL1998760 0.77 HDAC4 (0.44) CYP1A2GAAANPEPNOTUMTSHR
SCHEMBL28859675 0.75 CYP1A2 (0.64) CYP1A2IDO1TSHRHSD17B10PKM
SCHEMBL2246761 0.75 GAA (0.47) CYP1A2GAANOTUMTSHRHSD17B10
SCHEMBL19984866 0.75 CYP1A2 (0.49) CYP1A2GAANOTUMIDO1TSHR
SCHEMBL11831561 0.75 MAPT (0.58) ANPEPALOX15HTR2AHRH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019175025-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-09-19 WO disclosed