Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 18/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21367135 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3ADORA1RAPGEF3 | |
| SCHEMBL24489756 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3ADORA1RAPGEF3 | |
| SCHEMBL21356309 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3ADORA1RAPGEF3 | |
| SCHEMBL21367163 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3ADORA1RAPGEF3 | |
| SCHEMBL18026291 | 1.00 | PRMT5 (0.41) | PRMT5WDR77ADORA3ADORA1RAPGEF3 | |
| SCHEMBL18009869 | 0.90 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL18009711 | 0.86 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL18009766 | 0.85 | PRMT5 (0.43) | PRMT5WDR77RAPGEF3 | |
| SCHEMBL7680471 | 0.84 | PI4KA (0.46) | PRMT5WDR77ADORA3ADORA1 | |
| SCHEMBL6572792 | 0.84 | PI4KA (0.46) | PRMT5WDR77ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178368-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2019-09-19 | — | — | WO | disclosed |