Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 15/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21369451 | 0.94 | OGA (0.46) | OGASMN1; SMN2ACKR3ALDH1A1 | |
| SCHEMBL21369603 | 0.87 | OGA (0.58) | OGA | |
| SCHEMBL27099999 | 0.84 | OGA (0.37) | OGASMN1; SMN2ACKR3PSEN1PSEN2 | |
| SCHEMBL21369605 | 0.83 | JAK2 (0.31) | — | |
| SCHEMBL21370126 | 0.81 | OGA (0.62) | OGA | |
| SCHEMBL21370129 | 0.81 | OGA (0.62) | OGA | |
| SCHEMBL28569607 | 0.81 | OGA (0.62) | OGA | |
| SCHEMBL21370046 | 0.81 | OGA (0.62) | OGA | |
| SCHEMBL21370125 | 0.81 | OGA (0.62) | OGA | |
| SCHEMBL21369450 | 0.81 | OGA (0.62) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |