Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2137138 | 1.00 | MEN1 (0.33) | MEN1KMT2ALMNA | |
| SCHEMBL2137142 | 0.89 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL242105 | 0.78 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL2115863 | 0.78 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL1970697 | 0.74 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL2137284 | 0.74 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL2113307 | 0.73 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL1966960 | 0.73 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL2113136 | 0.71 | NPC1 (0.36) | MEN1KMT2ALMNA | |
| SCHEMBL241736 | 0.71 | NPC1 (0.36) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148414-B2 | Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use | XENOPORT, INC. (US) | 2012-04-03 | — | — | US | claimed |