SCHEMBL2137236

SCHEMBL2137236

C=CCCC(CC=C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
CPA1 P15085 1/20 0.52
TBXAS1 P24557 1/20 0.40
ABCC4 O15439 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.38
SLC6A3 Q01959 2/20 0.36
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FOLH1 Q04609 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18131874 0.88 CHRM1 (0.46) GRIK1GRIK2CPA1ABCC4MAPT
SCHEMBL2135519 0.87 GRIK1 (0.50) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL11753937 0.84 MAPT (0.53) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL16041974 0.84 MAPT (0.53) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL891727 0.83 GRIK1 (0.64) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL8031351 0.82 GRIK1 (0.53) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL28947258 0.81 GRIK1 (0.45) GRIK1GRIK2CPA1TBXAS1MAPT
SCHEMBL6050002 0.80 GRIK1 (0.75) GRIK1GRIK2CPA1TBXAS1ABCC4
SCHEMBL13258636 0.80 GRIK1 (0.57) GRIK1GRIK2CPA1TBXAS1CYP2C19
SCHEMBL5494036 0.80 ABCC4 (0.43) GRIK1GRIK2CPA1TBXAS1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684341-A Double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2025-03-25 CN disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-111433235-B Capped double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
CN-111448200-A Dual head organoaluminum compositions 陶氏环球技术有限责任公司 2020-07-24 CN disclosed
CN-111433235-A Capped dual head organoaluminum compositions 陶氏环球技术有限责任公司 2020-07-17 CN disclosed
EP-3519474-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2019-08-07 EP disclosed
EP-3519456-A1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-07 EP disclosed
WO-2018064546-A1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
WO-2018064540-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
EP-2450361-B1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF MITSUI CHEMICALS INC (JP) 2017-10-25 EP disclosed
US-8791284-B2 Organometallic compound and production method thereof MITSUI CHEMICALS, INC. (JP) 2014-07-29 US disclosed
EP-2450361-A1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF Mitsui Chemicals, Inc. (JP) 2012-05-09 EP disclosed
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS, INC. 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 GRIK1 4282/4885GRIK2 3829/4885CPA1 2190/4885
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF SLC39A11, AP2M1, AP1M1 GRIK1 107/4885GRIK2 398/4885CPA1 4470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.