Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372395 | 0.92 | TOP2A (0.32) | TOP2A | |
| SCHEMBL335589 | 0.82 | TOP2A (0.44) | TOP2A | |
| SCHEMBL13299183 | 0.82 | TOP2A (0.44) | TOP2A | |
| SCHEMBL21371873 | 0.82 | TOP2A (0.32) | TOP2A | |
| SCHEMBL13114362 | 0.82 | TOP2A (0.33) | TOP2A | |
| SCHEMBL335482 | 0.80 | TOP2A (0.40) | TOP2A | |
| SCHEMBL12113946 | 0.78 | BRD4 (0.30) | — | |
| SCHEMBL3360410 | 0.76 | TOP2A (0.38) | TOP2A | |
| SCHEMBL21371930 | 0.73 | TOP2A (0.33) | TOP2A | |
| SCHEMBL13114517 | 0.69 | TOP2A (0.34) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639824-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-04-22 | — | — | EP | disclosed |
| EP-3182973-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-09-18 | — | — | EP | disclosed |