Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302864 | 0.85 | TDP1 (0.53) | TDP1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL3697210 | 0.83 | AKR1C1 (0.47) | TDP1ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9302871 | 0.83 | AKR1C1 (0.47) | TDP1ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL391036 | 0.74 | TDP1 (0.50) | TDP1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL391037 | 0.71 | AKR1C1 (0.44) | TDP1ALDH1A1MAPTCYP2D6CYP2C19 | |
| SCHEMBL3875454 | 0.70 | TDP1 (0.58) | TDP1ATMALDH1A1MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL31332428 | 0.69 | TDP1 (0.57) | TDP1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL2334095 | 0.67 | CYP2D6 (0.41) | TDP1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL444728 | 0.67 | CYP2D6 (0.61) | TDP1ALDH1A1MAPTCYP1A2CYP2D6 | |
| Hydrogen Peroxide SCHEMBL28730771 | 0.67 | CYP2D6 (0.61) | TDP1ALDH1A1MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101231-A1 | Polymer Composition prepared from acrylic polymer grafted with a functionalized block copolymers | KRATON POLYMERS U.S. LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20100130670-A1 | END USE APPLICATIONS PREPARED FROM CERTAIN BLOCK COPOLYMERS | KRATON POLYMERS US LLC (US) | 2010-05-27 | — | — | US | disclosed |
| US-20090093584-A1 | End Use Applications Prepared From Certain Block Copolymers | KRATON POLYMERS U.S. LLC (US) | 2009-04-09 | — | — | US | disclosed |