Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978060 | 0.82 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL662501 | 0.82 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL665000 | 0.81 | TP53 (0.81) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL665069 | 0.74 | MAPT (0.81) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL18020440 | 0.73 | TP53 (0.67) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL664475 | 0.73 | MAPT (0.81) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL663583 | 0.72 | MAPT (0.82) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL30679122 | 0.70 | AR (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL29134727 | 0.70 | AR (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL30926969 | 0.69 | MAPT (0.73) | MAPTKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |