Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924698 | 0.87 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL12199140 | 0.85 | PARP10 (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL725405 | 0.84 | PARP10 (0.77) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL19777378 | 0.84 | MEN1 (0.53) | PARP10KMT2AMAPTMEN1RAB9A | |
| SCHEMBL10608864 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL8210785 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL4905240 | 0.84 | KMT2A (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL1546405 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL9663679 | 0.82 | PARP10 (0.81) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16050040 | 0.82 | PARP10 (0.74) | PARP10KMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292215-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | SPEROVIE BIOSCIENCES, INC. | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292215-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | STING1, CGAS, MYD88 | PARP10 1806/4885KMT2A 4445/4885MAPT 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.