Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | ADH1B | P00325 | 2/20 | 0.48 |
| ▸ | ADH1C | P00326 | 2/20 | 0.48 |
| ▸ | ADH1A | P07327 | 2/20 | 0.48 |
| ▸ | ADH4 | P08319 | 2/20 | 0.48 |
| ▸ | ADH7 | P40394 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31076288 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL9114450 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL296642 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL8536891 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL9544428 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL8534503 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL23925001 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL8533349 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL7508850 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B | |
| SCHEMBL31517108 | 1.00 | TSHR (0.70) | TSHRFAAHTRPV1ACE2ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| US-20190289886-A1 | SUBSTANCE MIXTURES | SYMRISE AG (DE) | 2019-09-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190289886-A1 | SUBSTANCE MIXTURES | PNN, NISCH, HES1 | TSHR 4289/4885FAAH 1438/4885TRPV1 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.