Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385177 | 0.89 | GFER (0.48) | GFERIDO1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL21381380 | 0.89 | IDO1 (0.52) | GFERIDO1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17729120 | 0.84 | CHRM4 (0.54) | IDO1MAPTTP53POLB | |
| SCHEMBL21400820 | 0.81 | IDO1 (0.59) | GFERIDO1 | |
| SCHEMBL17729117 | 0.81 | IDO1 (0.56) | IDO1CYP2C19 | |
| SCHEMBL21400743 | 0.81 | IDO1 (0.49) | GFERIDO1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL21400827 | 0.79 | IDO1 (0.56) | GFERIDO1 | |
| SCHEMBL21400821 | 0.79 | IDO1 (0.56) | GFERIDO1 | |
| SCHEMBL21400826 | 0.79 | IDO1 (0.56) | GFERIDO1 | |
| SCHEMBL28699360 | 0.74 | IDO1 (0.55) | IDO1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630043-B | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111630043-A | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |