Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379397 | 0.88 | CMA1 (0.42) | TP53ALDH1A1CMA1TSHRKMT2A | |
| SCHEMBL21381480 | 0.88 | CMA1 (0.42) | TP53ALDH1A1CMA1TSHRKMT2A | |
| SCHEMBL21384901 | 0.88 | CMA1 (0.42) | ALDH1A1CMA1TSHRKMT2AMEN1 | |
| SCHEMBL20379399 | 0.88 | CMA1 (0.42) | ALDH1A1CMA1TSHRKMT2AMEN1 | |
| SCHEMBL20379080 | 0.88 | CMA1 (0.43) | TP53ALDH1A1CMA1TSHRKMT2A | |
| SCHEMBL21381513 | 0.88 | CMA1 (0.39) | ALDH1A1CMA1KMT2AMEN1MAPT | |
| SCHEMBL20379057 | 0.78 | CMA1 (0.48) | ALDH1A1CMA1TSHRKMT2AMAPT | |
| SCHEMBL20379413 | 0.76 | CMA1 (0.46) | ALDH1A1CMA1TSHRKMT2AMEN1 | |
| SCHEMBL21381492 | 0.74 | KMT2A (0.41) | MGLLTP53ALDH1A1TSHRKMT2A | |
| SCHEMBL20379403 | 0.74 | CMA1 (0.43) | ALDH1A1CMA1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3568133-B1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH ZUERICH (CH) | 2023-12-13 | — | — | EP | claimed |
| EP-3768673-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2021-01-27 | — | — | EP | claimed |
| WO-2019179890-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH ZURICH (CH) | 2019-09-26 | — | — | WO | claimed |
| EP-3768673-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH Zurich (CH) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019179890-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH ZURICH (CH) | 2019-09-26 | — | — | WO | disclosed |