Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.45 |
| ▸ | GRM6 | O15303 | 2/20 | 0.45 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21381531 | 1.00 | GRM8 (0.45) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL10142221 | 0.89 | GRM8 (0.48) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL28573530 | 0.83 | PTGS1 (0.35) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL23635934 | 0.83 | PTGS1 (0.35) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL17789224 | 0.81 | SLC1A2 (0.44) | CYP1A2GSRGRIK1GRM5SLC1A3 | |
| SCHEMBL1158176 | 0.81 | SLC1A2 (0.44) | CYP1A2GSRGRIK1GRM5SLC1A3 | |
| SCHEMBL2405601 | 0.80 | PTGS1 (0.46) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL13684358 | 0.79 | PTGS1 (0.38) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL11883461 | 0.79 | GSR (0.42) | GRM8GRM6GRM7GRM4CYP1A2 | |
| SCHEMBL2729297 | 0.79 | GSR (0.47) | GRM8GRM6GRM7GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179985-A1 | INHIBITORS OF MINT AND USES THEREOF | UNIVERSITY OF COPENHAGEN (DK) | 2019-09-26 | — | — | WO | claimed |
| WO-2019179985-A1 | INHIBITORS OF MINT AND USES THEREOF | UNIVERSITY OF COPENHAGEN (DK) | 2019-09-26 | — | — | WO | disclosed |