Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.66 |
| ▸ | CSF1R | P07333 | 2/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.66 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ABL1 | P00519 | 5/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | BLK | P51451 | 1/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634986 | 1.00 | KIT (0.66) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391367 | 0.96 | KIT (0.68) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391331 | 0.92 | KIT (0.77) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391362 | 0.90 | KIT (0.59) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391329 | 0.89 | KIT (0.60) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21381312 | 0.89 | KIT (0.58) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL29634979 | 0.89 | KIT (0.58) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391407 | 0.89 | KIT (0.55) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391402 | 0.89 | KIT (0.55) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL20695981 | 0.88 | KIT (0.86) | KITCSF1RPDGFRBDDR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283160-B | PDGFR kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-04-29 | — | — | CN | disclosed |
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |