Methane

Methane

SCHEMBL21386924

C.COc1ccnc(-c2cc(OC)ccn2)c1

nearest known ligand 0.95

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.95
CCR5 P51681 2/20 0.95
CCR8 P51685 2/20 0.95
NOS3 P29474 2/20 0.59
NOS1 P29475 2/20 0.59
NOS2 P35228 2/20 0.59
PLAU P00749 1/20 0.53
SYK P43405 6/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2E1 P05181 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP4B1 P13584 1/20 0.46
CYP2B6 P20813 1/20 0.46
CYP3A5 P20815 1/20 0.46
CYP2A7 P20853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395249 0.98 CCR1 (1.00) CCR1CCR5CCR8NOS3NOS1
SCHEMBL182529 0.98 CCR1 (1.00) CCR1CCR5CCR8NOS3NOS1
SCHEMBL9135460 0.95 CCR1 (0.95) CCR1CCR5CCR8NOS3NOS1
Hydrochloric Acid SCHEMBL29903189 0.95 CCR1 (0.95) CCR1CCR5CCR8NOS3NOS1
SCHEMBL8746042 0.95 CCR1 (0.95) CCR1CCR5CCR8NOS3NOS1
SCHEMBL28212407 0.95 CCR1 (0.95) CCR1CCR5CCR8NOS3NOS1
Bromide SCHEMBL29619549 0.93 CCR1 (0.91) CCR1CCR5CCR8NOS3NOS1
Methane SCHEMBL21386756 0.90 CCR1 (0.77) CCR1CCR5CCR8NOS3NOS1
SCHEMBL30957052 0.89 CCR1 (0.83) CCR1CCR5CCR8NOS3NOS1
SCHEMBL196913 0.89 CCR1 (0.83) CCR1CCR5CCR8NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2854948-B1 METAL-BASED THIOPHENE PHOTODYNAMIC COMPOUNDS AND THEIR USE MCFARLAND SHERRI ANN (CA) 2019-09-25 EP disclosed