SCHEMBL21387340

SCHEMBL21387340

Bc1ccn2c(C(=O)Nc3cc(-c4noc(C5CN(C(=O)OC)C5)n4)ccc3C)cnc2c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14738895 0.93 KIT (0.77) KIT
SCHEMBL27338941 0.92 KIT (0.67) KIT
SCHEMBL14739838 0.92 KIT (0.66) KIT
SCHEMBL14755315 0.92 KIT (0.66) KIT
SCHEMBL14739909 0.92 KIT (0.78) KIT
SCHEMBL14740165 0.91 KIT (0.78) KIT
SCHEMBL21387399 0.90 KIT (0.62) KIT
SCHEMBL14739613 0.90 KIT (0.71) KIT
SCHEMBL27336728 0.90 KIT (0.65) KIT
SCHEMBL21387496 0.90 KIT (0.66) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2751104-B1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS NOVARTIS AG (CH) 2019-09-25 EP disclosed