Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372434 | 0.94 | KIT (0.81) | KIT | |
| SCHEMBL14739360 | 0.93 | KIT (0.80) | KIT | |
| SCHEMBL14739283 | 0.91 | KIT (1.00) | KIT | |
| SCHEMBL14741385 | 0.90 | KIT (0.79) | KIT | |
| SCHEMBL14747214 | 0.88 | KIT (0.74) | KIT | |
| SCHEMBL14738918 | 0.86 | KIT (1.00) | KIT | |
| SCHEMBL21387391 | 0.86 | KIT (0.66) | KIT | |
| SCHEMBL21387390 | 0.85 | KIT (0.81) | KIT | |
| SCHEMBL14757523 | 0.85 | KIT (0.71) | KIT | |
| SCHEMBL21387413 | 0.83 | KIT (0.83) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751104-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-09-25 | — | — | EP | disclosed |