Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14755309 | 0.92 | KIT (0.68) | KIT | |
| SCHEMBL14739577 | 0.91 | KIT (0.79) | KIT | |
| SCHEMBL14753308 | 0.91 | KIT (0.70) | KIT | |
| SCHEMBL14758862 | 0.91 | KIT (0.67) | KIT | |
| SCHEMBL14752834 | 0.91 | KIT (0.70) | KIT | |
| SCHEMBL14740425 | 0.91 | KIT (0.77) | KIT | |
| SCHEMBL14740068 | 0.90 | KIT (0.79) | KIT | |
| SCHEMBL14740239 | 0.90 | KIT (0.65) | KIT | |
| SCHEMBL14739392 | 0.89 | KIT (0.64) | KIT | |
| SCHEMBL14739121 | 0.88 | KIT (0.82) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751104-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-09-25 | — | — | EP | disclosed |