Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 4/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | NPPA | P01160 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387648 | 0.86 | CTPS1 (0.38) | CTPS1 | |
| SCHEMBL21392146 | 0.80 | CTPS1 (0.32) | CTPS1 | |
| SCHEMBL22924763 | 0.78 | CTPS1 (0.50) | CTPS1 | |
| SCHEMBL29228050 | 0.77 | CTPS1 (0.49) | CTPS1 | |
| Potassium SCHEMBL30882879 | 0.77 | CTPS1 (0.49) | CTPS1 | |
| Lithium SCHEMBL30518335 | 0.71 | KMT2A (0.33) | — | |
| Potassium Ion SCHEMBL21373800 | 0.70 | CTPS1 (0.49) | CTPS1 | |
| SCHEMBL21373755 | 0.69 | CTPS1 (0.50) | CTPS1 | |
| SCHEMBL21392137 | 0.64 | HPGD (0.33) | — | |
| SCHEMBL30518337 | 0.64 | HPGD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543232-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | Step Pharma S.A.S. (FR) | 2019-09-25 | — | — | EP | disclosed |