Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 14/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21373818 | 0.85 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL30528848 | 0.85 | CTPS1 (1.00) | CTPS1 | |
| SCHEMBL21387687 | 0.85 | CTPS1 (0.76) | CTPS1 | |
| SCHEMBL21387616 | 0.84 | CTPS1 (0.64) | CTPS1 | |
| SCHEMBL21387678 | 0.81 | CTPS1 (0.75) | CTPS1 | |
| SCHEMBL21387629 | 0.79 | CTPS1 (0.75) | CTPS1ABCB1 | |
| SCHEMBL21387685 | 0.79 | CTPS1 (0.76) | CTPS1 | |
| SCHEMBL21387656 | 0.78 | CTPS1 (0.73) | CTPS1 | |
| SCHEMBL21387646 | 0.77 | CTPS1 (0.70) | CTPS1 | |
| SCHEMBL21387655 | 0.76 | CTPS1 (0.72) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543232-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | Step Pharma S.A.S. (FR) | 2019-09-25 | — | — | EP | disclosed |