⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14127273 | 1.00 | — | — | |
| SCHEMBL882903 | 1.00 | — | — | |
| SCHEMBL37100 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL15668481 | 0.97 | TSHR (0.55) | — | |
| SCHEMBL1705373 | 0.97 | TSHR (0.55) | — | |
| Ammonia Solution, Strong SCHEMBL20561016 | 0.97 | TSHR (0.55) | — | |
| Methane SCHEMBL8615254 | 0.97 | TSHR (0.55) | — | |
| Bromide SCHEMBL28550538 | 0.97 | TSHR (0.55) | — | |
| SCHEMBL4935048 | 0.94 | TSHR (0.52) | — | |
| SCHEMBL8750450 | 0.89 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230170-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2025-07-17 | — | — | US | disclosed |
| US-12264165-B2 | Process for the stereoselective preparation of chiral 2-[(hetero) arylalkylsulfanyl]pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2025-04-01 | — | — | US | disclosed |
| CN-118344296-A | Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom | 坎塞拉有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112218853-B | Process for the stereoselective preparation of chiral 2- [ (hetero) aralkylthio ] pyrimidines and products obtainable therefrom | 坎塞拉有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117945983-A | Intermediate for preparing CDK4/6 active compound and preparation method thereof | 创沐医药科技(上海)有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-20230322807-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322807-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2023-10-12 | — | — | US | disclosed |
| US-20230322807-A1 | Process for the Steroselective Preparation of Chiral 2-[(Hetero)Arylalkylsulfanyl]Pyrimidines and Products Obtainable Therefrom | KANCERA AB (SE) | 2023-10-12 | — | — | US | disclosed |
| US-11691988-B2 | Process for the stereoselective preparation of chiral 2-[(hetero)arylalkylsulfanyl]pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2023-07-04 | — | — | US | disclosed |
| US-11691988-B2 | Process for the stereoselective preparation of chiral 2-[(hetero)arylalkylsulfanyl]pyrimidines and products obtainable therefrom | KANCERA AB (SE) | 2023-07-04 | — | — | US | disclosed |
| US-20110071126-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. | 2011-03-24 | — | — | US | disclosed |
| US-20110071126-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. | 2011-03-24 | — | — | US | disclosed |
| CN-101193897-B | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives | ASTRAZENECA AB | 2010-12-01 | — | — | CN | disclosed |
| CN-101193898-B | Novel 5,7-disubstituted [1,3]thiazolo[4,5-d]pyrimidin-2(3H)-one derivatives | ASTRAZENECA AB | 2010-12-01 | — | — | CN | disclosed |
| EP-1869056-B1 | NOVEL 5-SUBSTITUTED 7-AMINO-Ý1,3¨THIAZOLOÝ4,5-D¨PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-11-10 | — | — | EP | disclosed |
| WO-2010105179-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| US-20090124637-A1 | Novel 5,7-Disubstituted [1,3]Thiazolo[4,5-D]Pyrimidin-2(3H)-One Derivatives 794 | ASTRAZENECA AB (SE) | 2009-05-14 | — | — | US | disclosed |
| US-20080214578-A1 | Novel 5-Substituted 7-Amino-[1,3]Thiazolo[4,5-D]Pyrimidine Derivatives 793 | ACTURUM REAL ESTATE AB (SE) | 2008-09-04 | — | — | US | disclosed |
| CN-101193897-A | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives | ASTRAZENECA AB (SE) | 2008-06-04 | — | — | CN | disclosed |
| CN-101193898-A | Novel 5,7-disubstituted [1,3]thiazolo[4,5-d]pyrimidin-2(3H)-one derivatives | ASTRAZENECA AB (SE) | 2008-06-04 | — | — | CN | disclosed |