Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26752479 | 1.00 | CACNA1H (0.44) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL24795882 | 0.91 | EPHX1 (0.46) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL21389393 | 0.91 | EPHX1 (0.46) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL24796130 | 0.85 | TDP1 (0.45) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL13528300 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13528427 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL14344456 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13528455 | 0.82 | TDP1 (0.43) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL21389173 | 0.81 | TDP1 (0.42) | CACNA1HTDP1DRD2EPHX1ALDH1A1 | |
| SCHEMBL21389215 | 0.80 | TDP1 (0.46) | CACNA1HTDP1DRD2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | CACNA1H 1290/4885TDP1 3206/4885DRD2 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.